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1.
Int J Mol Sci ; 23(14)2022 Jul 21.
Article in English | MEDLINE | ID: covidwho-1957345

ABSTRACT

The aim of this Special Edition is to highlight the exponential work performed in the field of antimicrobial material research from the beginning of the current COVID-19 pandemic [...].


Subject(s)
Anti-Infective Agents , COVID-19 Drug Treatment , Anti-Bacterial Agents/pharmacology , Anti-Bacterial Agents/therapeutic use , Anti-Infective Agents/pharmacology , Anti-Infective Agents/therapeutic use , Humans , Pandemics
2.
Int J Mol Sci ; 23(3)2022 Jan 21.
Article in English | MEDLINE | ID: covidwho-1650511

ABSTRACT

International interest in metal-based antimicrobial coatings to control the spread of bacteria, fungi, and viruses via high contact human touch surfaces are growing at an exponential rate. This interest recently reached an all-time high with the outbreak of the deadly COVID-19 disease, which has already claimed the lives of more than 5 million people worldwide. This global pandemic has highlighted the major role that antimicrobial coatings can play in controlling the spread of deadly viruses such as SARS-CoV-2 and scientists and engineers are now working harder than ever to develop the next generation of antimicrobial materials. This article begins with a review of three discrete microorganism-killing phenomena of contact-killing surfaces, nanoprotrusions, and superhydrophobic surfaces. The antimicrobial properties of metals such as copper (Cu), silver (Ag), and zinc (Zn) are reviewed along with the effects of combining them with titanium dioxide (TiO2) to create a binary or ternary contact-killing surface coatings. The self-cleaning and bacterial resistance of purely structural superhydrophobic surfaces and the potential of physical surface nanoprotrusions to damage microbial cells are then considered. The article then gives a detailed discussion on recent advances in attempting to combine these individual phenomena to create super-antimicrobial metal-based coatings with binary or ternary killing potential against a broad range of microorganisms, including SARS-CoV-2, for high-touch surface applications such as hand rails, door plates, and water fittings on public transport and in healthcare, care home and leisure settings as well as personal protective equipment commonly used in hospitals and in the current COVID-19 pandemic.


Subject(s)
Anti-Infective Agents/pharmacology , COVID-19/prevention & control , Coated Materials, Biocompatible/pharmacology , Metals/chemistry , Touch , Animals , Anti-Infective Agents/chemical synthesis , Anti-Infective Agents/chemistry , COVID-19/transmission , Coated Materials, Biocompatible/chemical synthesis , Coated Materials, Biocompatible/chemistry , Humans , Pandemics , Personal Protective Equipment/microbiology , Personal Protective Equipment/virology , SARS-CoV-2/drug effects , Surface Properties , Viruses/drug effects
3.
Additive Manufacturing ; : 102378, 2021.
Article in English | ScienceDirect | ID: covidwho-1446339

ABSTRACT

Fused deposition modelling (FDM) is an advanced 3D printing technique for the manufacture of plastic materials. The ease of use, prototyping accuracy and low cost makes it a widely used additive manufacturing technique. FDM creates 3D structures through the layer-by-layer melt-extrusion of a plastic filament. The production of a printed structure involves the generation of a digital design of the model by 3D design software and its execution by the printer until the complete model is reproduced. This review presents the current status of FDM, how to handle and operate FDM printers, industry standards of printing, the types of filaments that can be used, the post-processing treatments, advantages, and limitations as well as an overview of the increasing application fields of FDM technology. The application areas of FDM are endless, including biomedicine, construction, automotive, aerospace, acoustics, textiles, and occupational therapy amongst others. Even during the current Coronavirus disease (COVID-19) pandemic, FDM has helped to fabricate face masks, ventilators and respiratory systems, respiratory valves, and nasopharyngeal swabs for COVID-19 diagnosis. FDM 3D and 4D printing can produce polymeric and composite structures of various designs, and compositions in a range of materials according to the desired application. The review concludes by discussing the future prospects for FDM.

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